Dr. Carlos Mota

Assistant Professor in the Department of Complex Tissue Regeneration, MERLN Institute for Technology-inspired Regenerative Medicine, Maastricht University

Can you tell us about who you are and what your role in BIRDIE is?

My name is Carlos Mota. I am an engineer by training with a PhD in biomaterials. I am the BIRDIE project coordinator and WP2 and WP6 leader. The WP2 is focused on the establishment of differentiation of renal progenitors derived from human induced pluripotent stem cells (hiPSCs) and the team of the University of Maastricht (the Netherlands), is also focusing on the development of hydrogel biomaterial for bioprinting and on-chip tubulointerstitium models. WP6 is focused on the management activities and interface with the European commission.

What is the focus of the research that you are leading?

My team is establishing differentiation protocols to generate renal cell progenitors from hiPSCs. Furthermore, we are also developing hydrogel biomaterial inks for bioprinting. The cells and biomaterials will be combined and bioprinted to achieve the aimed humanized kidney tubulointerstitium model.

What is your team working on right now?

We are currently refining both cell protocols and biomaterials to achieve a physiologically relevant response of cells after bioprinting. We aim to integrate the bioprinting constructs in an organ on chip model in the next phases of the project.

Read more about BIRDIE’s contribution to kidney health

BIRDIE building a foundation for better kidney health

Kidney diseases affects approximately one in every ten individuals globally and Chronic Kidney Disease (CKD) is predicted to become the 5th leading cause of death worldwide. The main causes for CKD include diabetes and high blood pressure, as well as viral infection and immune system diseases. Today, therapeutic options offered to patients are still limited…